منابع مشابه
Prevalence of Vancomycin Resistance in Methicillin-Resistant Staphylococcus Aureus
Background & Aims: Staphylococcus aureus is one of the most common pathogens in nosocomial infections. Vancomycin is the most important therapeutic drug of choice for treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains. Therefore, vancomycin-resistant Staphylococcus aureus (VRSA) or vancomycin-intermediate Staphylococcus aureus (VISA) strains are warning...
متن کاملModeling of the Bacterial Mechanism of Methicillin-Resistance by a Systems Biology Approach
BACKGROUND A microorganism is a complex biological system able to preserve its functional features against external perturbations and the ability of the living systems to oppose to these external perturbations is defined "robustness". The antibiotic resistance, developed by different bacteria strains, is a clear example of robustness and of ability of the bacterial system to acquire a particula...
متن کاملMechanism of Resistance, Phenotyping and Genotyping of Methicillin Resistant Staphylococcus aureus: A Review
Staphylococcus aureus causes a variety of suppurative (pus-forming) infections and toxinoses in humans. It causes superficial skin lesions such as boils, styes and furuncules; more serious infections such as pneumonia, mastitis, phlebitis, meningitis, and urinary tract infections; and deep-seated infections, such as osteomyelitis and endocarditis. S. aureus is a major cause of hospital acquired...
متن کاملEagle-type methicillin resistance: new phenotype of high methicillin resistance under mec regulator gene control.
We report a novel phenotype of methicillin resistance, designated "Eagle-type" resistance, which is characteristic in its resistance to high concentrations of methicillin (64 to 512 microg/ml) and susceptibility to low concentrations of methicillin (2 to 16 microg/ml). The type of resistance was expressed in mutant strains selected with high concentrations (e.g., 128 to 512 microg/ml) of methic...
متن کاملDetection of methicillin/oxacillin resistance in staphylococci.
Methicillin/oxacillin-resistant staphylococci are heterogeneous in their expression of resistance to beta-lactam agents and the test conditions have a major effect on the expression and therefore the detection of resistance. Conflicting recommendations regarding the most reliable method for routine use are partly related to differences between strains and there may be a variable interaction bet...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1986
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/18.4.435